Enantioselective domino reaction of CO2, amines and allyl chlorides under iridium catalysis: formation of allyl carbamates.
نویسندگان
چکیده
The enantioselective domino reaction between CO2 (1 atm), amines and linear allyl chlorides in the presence of an iridium complex, DABCO and toluene at 15 °C was realized, which gave branched allyl carbamates in acceptable to high yields with up to excellent regioselectivity (99/1) and 94% ee. This is the first example of the synthesis of chiral allyl carbamates through catalytic domino reactions using CO2.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 34 شماره
صفحات -
تاریخ انتشار 2014